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KMID : 0370219820260030175
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Yakhak Hoeji
1982 Volume.26 No. 3 p.175 ~ p.180
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A Study on Possible Interaction between Nicotine-specific Nitrosamines and Nucleic Acid Bases by Molecular Orbital Theory (I) N’-nitrosonornicotine and Its Metabolic Intermediates
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Rhee Jong-Dal
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Abstract
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The intermediate of N’-nitrosonornicotine may bind to the guanine moiety of a G-C base pair. The hydrogen bond of the base pair may be broken and a new hydrogen bond can form between the intermediate and the guanine. It results in the "short" type of DNA repair.NA repair.
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